Global Trisenox (Arsenic Trioxide) Market 2020

                                          
Trisenox® (arsenic trioxide) is indicated for induction of remission and consolidation in patients with acute promyelocytic leukemia (APL) who are refractory to or have relapsed from, retinoid and anthracycline chemotherapy.

Arsenic trioxide is a chemotherapeutic agent of an idiopathic function used to treat leukemia that is unresponsive to first-line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. The mechanism of action of Arsenic Trioxide is not completely understood. Arsenic trioxide causes morphological changes and DNA fragmentation characteristic of apoptosis in NB4 human promyelocytic leukemia cells in vitro. Arsenic trioxide also causes damage or degradation of the fusion protein PML/RAR-alpha. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects. The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.

APL is a rare form of leukemia (cancer of the white blood cells) caused by a genetic ‘translocation’ (when there is a swap of genes between two chromosomes). The translocation affects the way the white blood cells grow, and as a result, they lack the ability to use retinoic acid (vitamin A). Patients with APL are normally treated with retinoids (substances derived from vitamin A).

This report studies the global Trisenox (arsenic trioxide) market status and forecast, categorizes the global Trisenox (arsenic trioxide) market size (value & volume) by manufacturers, type, application, and region. This report focuses on the top manufacturers in North America, Europe, Japan, China, and other regions (India, Southeast Asia).

The major manufacturers covered in this report


 	
Teva
 	
Fresenius Kabi
 	
Nexus Pharmaceuticals
 	
Medac
 	
Cadila Healthcare Limited
 	
Ingenus Pharmaceuticals, LLC
 	
Amring Pharmaceuticals Inc.
 	
Zydus Pharmaceuticals (USA) Inc.

Geographically, this report studies the top producers and consumers, focuses on product capacity, production, value, consumption, market share and growth opportunity in these key regions, covering

 	
North America
 	
Europe
 	
Asia-Pacific
 	
The Middle East and Africa

On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split into

 	
Arsenic trioxide 1mg/mL
 	
Arsenic trioxide 2 mg/ml

On the basis of the end users/applications, this report focuses on the status and outlook for major applications/end users, consumption (sales), market share and growth rate for each application, including

 	
Adult
 	
Children

In October 2020, medac Gesellschaft für klinische Spezialpräparate mbH received marketing authorization valid throughout the European Union for Arsenic trioxide medac(arsenic trioxide) which is a medicine used to treat adults (aged 18 years or over) with acute promyelocytic leukaemia (APL). Arsenic trioxide medac is a generic medicine. This means that Arsenic trioxide medac contains the same active substance and works in the same way as a reference medicine already authorised in the EU called Trisenox. Arsenic trioxide medac contains the active substance arsenic trioxide. The European Medicines Agency concluded that, in accordance with EU requirements, Arsenic trioxide medac has been shown to be comparable to Trisenox. Therefore, the Agency’s view was that, as for Trisenox, the benefits of Arsenic trioxide medac outweigh the identified risks and it can be authorised for use in the EU.

The study objectives of this report are:

 	
To analyze and study the global Trisenox (arsenic trioxide) capacity, production, value, consumption, status (2015-2020) and forecast (2021-2029);
 	
Focuses on the key Trisenox (arsenic trioxide) manufacturers, to study the capacity, production, value, market share and development plans in the future.
 	
Focuses on the global key manufacturers, to define, describe and analyze the market competition landscape, SWOT analysis.
 	
To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
 	
To identify significant trends and factors driving or inhibiting market growth.
 	
To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
 	
To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
 	
To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
 	
To strategically profile the key players and comprehensively analyze their growth strategies.

Key Stakeholders

 	
Trisenox (arsenic trioxide) Manufacturers
 	
Trisenox (arsenic trioxide) Distributors/Traders/Wholesalers
 	
Trisenox (arsenic trioxide) Subcomponent Manufacturers
 	
Industry Association
 	
Downstream Vendors

Available Customizations

 	
Regional and country-level analysis of the Trisenox (arsenic trioxide) market, by end-use.
 	
Detailed analysis and profiles of additional market players.