Spatial Genomics & Transcriptomics Market Size, Sector / Industry Report & Analysis, 2025 (Includes Business Impact of COVID-19)

                                          
Abstract, Snapshot, Market Analysis & Market Definition: Global Spatial Genomics & Transcriptomics Market


The global Spatial Genomics & Transcriptomics market size is projected to reach US$ 286.94 million by 2026, from US$ 175.88 million in 2020, at a CAGR of 8.5% during 2021-2026. Spatial genomics & transcriptomics is a relatively new discipline that involves the determination of high-throughput data pertaining to the organizational structure of cell content from tissue and cell specimens. Conventional genomic techniques lose positional information of the nucleic acid content, which has been addressed by the advent of this technology. Moreover, rapid advancements in the genomics arena, ranging from tissue sequencing to single-cell sequencing, have significantly benefitted spatial genomic sequencing techniques. This is because single cell sequencing enables the identification of the spatial origin of cells to characterize complex tissues.

Spatial patterns of the genome have been identified for several medical conditions, which has resulted in the implementation of spatial information as a diagnostic biomarker for various diseases. Growing demand for biomarkers, which enable differentiation of benign tumor from the malignant tumor with higher accuracy, boosts the demand for spatial genomic analysis as a cancer diagnostic tool.

The high adoption rate of in situ sequencing techniques for identification of the spatial distribution of reads in a sample drives the market. Market participants are undertaking efforts to address the increasing demand for advanced sequencing techniquesto study architectural patterns.

For instance, in February 2018, Dovetail LLC launched Dovetail Hi-C and Fix-C with Selva structural variation detection software. This is the first commercial service for the study 3-D structure genome structure of diseased specimens. Moreover, an increase in funding initiatives for genomic and transcriptomic studies has created significant opportunities for companies to expand their businesses.

For instance, in January 2018, ReadCoor received a grant from the Silicon Valley Community Foundation (DAF) and Chan Zuckerberg Initiative for spatial mapping of cortical cells. Similarly, in April 2017, Seven Bridges invested in the Spatial Transcriptomics AB for the development of a set of tools for the visualization of gene expression within tissue samples for biomedical analysis.

Market Segmentation, Outlook & Viewpoint: Global Spatial Genomics & Transcriptomics Market

Technology Market Segmentation & Outlook (Revenue, USD Thousand, 2014 - 2025)

Spatial Transcriptomics

  
Sequencing-Based Methods
  
Laser Capture Microdissection (LCM)
  
FFPE Tissue Samples
  
Others

Transcriptome In-Vivo Analysis (TIVA)

  
In Situ Sequencing
  
Microtomy Sequencing
  
IHC
  
Microscopy-based RNA Imaging Techniques
  
Single Molecule RNA Fluorescence In-Situ Hybridization (smFISH)
  
Padlock Probes/ Rolling Circle Amplification
  
Branched DNA Probes

Spatial Genomics

  
FISH
  
Microscopy-based Live DNA Imaging
  
Genome Perturbation Tools
  
Massively-Parallel Sequencing
  
Biochemical Techniques
  
Others

Product Market Segmentation & Outlook (Revenue, USD Thousand, 2014 - 2025)

Instruments

  
By Mode
  
Automated
  
Semi-automated
  
Manual
  
By Type
  
Sequencing Platforms
  
IHC
  
Microscopy
  
Flow Cytometry
  
Mass Spectrometry
  
Others

Consumables

Software

  
Bioinformatics Tools
  
Imaging Tools
  
Storage and Management Databases

End-use Type Market Segmentation & Outlook (Revenue, USD Thousand, 2014 - 2025)

  
Translational Research
  
Academic Customers
  
Diagnostic Customers
  
Pharmaceutical Manufacturer

Key Players, Recent Developments & Regional Insights: Global Spatial Genomics & Transcriptomics Market

Revenue flow from the consumables segment was estimated to be highest in 2018. Attributing factors include wide availability of reagents and kits, increased usage rate, and frequent purchase of consumables, which results in higher penetration of consumables to run the instruments. Numerous genetics-related research studies are integrating robust software solutions for data management and interpretation. The introduction and employment of automated data analysis software by companies is anticipated to result in the lucrative growth of software.

End-use Insights

The translational research segment accounted for the dominant revenue share in 2018 and is anticipated to continue this trend throughout the forecast period. This can be attributed to the wide application of spatial genomics techniques in translational studies to analyze the behavior of human tissues and cells from other individuals.

In addition, several research organizations have introduced study programs, such as BRAIN Initiative launched by NIH, to leverage the application of spatial transcriptomic in the field of disease diagnosis. Furthermore, neuroscientists have started the implementation of single-cell transcriptomics research in order to understand the architecture of nervous tissues.

Academic customers are expected to emerge as a lucrative source of revenue during the forecast period owing to the increase in sequencing-based research programs in universities. Furthermore, continuous funding programs to accelerate research projects in universities drives the segment progression.

Regional Insights

North America dominated the market by revenue due to increasing adoption of solutions for spatial profiling in cancer research, coupled with rising focus on genomics-based R&D. For instance, the GeoMx platform by U.S.-based NanoString Technologies, Inc. has been implemented in more than 70 research projects, focusing on approximately 25 cancer types.

Asia Pacific is anticipated to register the highest CAGR due to rising investments by public and private agencies. For instance, in 2018, research involving prediction of gene regulatory networks from transcriptome datasets was jointly funded by Grant-in-Aid for Scientific Research from Japan Society for the Promotion of Science, Advanced Low Carbon Technology Research and Development Program (ALCA), and CREST by Japan Science and Technology Agency.

Spatial Genomics & Transcriptomics Market Share Insights

Some of the key participants operating in this market are 10x Genomics; Dovetail Genomics; Illumina, Inc.;S2 Genomics, Inc.; NanoString Technologies; Seven Bridges Genomic; Horizon Discovery Group plc; CARTANA AB; and Advanced Cell Diagnostics.

Mature players are involved in the development of novel platforms to maintain their market position. Funding from government bodies assist emerging players in broadening their product offerings. For instance, in June 2018, S2 Genomics received Phase I STTR grant from the National Institute of Health for the development of a singulator system for automated preparation of single nuclei.

Key Insights Covered: Global Spatial Genomics & Transcriptomics Market

1. North America, Europe, Asia Pacific, Middle East & Africa, Latin America market size (sales, revenue and growth rate) of Spatial Genomics & Transcriptomics industry.
2. Global major manufacturers" operating situation (sales, revenue, growth rate and gross margin) of Spatial Genomics & Transcriptomics industry.
3. Global major countries (United States, Canada, Germany, France, UK, Italy, Russia, Spain, China, Japan, Korea, India, Australia, New Zealand, Southeast Asia, Middle East, Africa, Mexico, Brazil, C. America, Chile, Peru, Colombia) market size (sales, revenue and growth rate) of Spatial Genomics & Transcriptomics industry.
4. SWOT analysis, New Project Investment Feasibility Analysis, Upstream raw materials and manufacturing equipment & Industry chain analysis of Spatial Genomics & Transcriptomics industry.
5. Global market size (sales, revenue) forecast by regions and countries from 2019 to 2024 of Spatial Genomics & Transcriptomics industry.

Research Methodology: Global Spatial Genomics & Transcriptomics Market

  
Data collection and base year analysis is done using data collection modules with large sample sizes. The market data is analyzed and forecasted using market statistical and coherent models. Also market share analysis and key trend analysis are the major success factors in the market report. To know more please Request a Sample Report.
  
Demand Side Primary Contributors: OEMs, Industrial Professionals, Researches, Suppliers and Distributors, Group Purchasing Organizations, Associations, Insurers, Universities, Technological Writers, Scientists, Promoters, Investors among others.
  
Supply Side Primary Contributors: Product Managers, Marketing Managers, C-Level Executives, Distributors, Market Intelligence, Regulatory Affairs Managers among other