Cancer Stem Cells Market Size & Analysis, Sector / Industry Report & Analysis, 2018-2025 (Includes Business Impact of COVID-19)

                                          
Abstract, Snapshot, Market Analysis & Market Definition: Global Cancer Stem Cells Market


The global cancer stem cells market size was valued at USD 679.5 million in 2016. The market is expected to expand at a CAGR of 9.98% during the forecast period. Currently, oncology therapeutics has entered a new era with conventional therapies such as radiotherapy, chemotherapy, & surgeries on one side and stem cell therapies on another side.
Over the past few years, stem cells are being successfully utilized in immuno-reconstitution and for replenishment of blood after tumor development or after tumor treatment. Furthermore, these cells have gained significant attention among healthcare entities for its employment as tools for delivery of anti-cancer agents as well as for tissue regeneration. A considerable number of entities have reported positive outcome of using this mode of tumor treatment.
 
While this therapy is receiving huge success in clinical oncology, a substantial number of published studies have mentioned cancer as “Cancer Stem Cell (CSC) disorder”. Due to introduction of this novel concept, an enormous potential for anti-CSCs therapeutics has been created.
This approach enables comprehensive investigation of essential as well as poorly understood clinical events in tumor initiation, propagation, relapse, and metastasis. This is considered as one of the major factors responsible for increasing interest in the cancer stem cell model.
There is an accumulating evidence that sheds light on existence of cancer stem cells and their role in conferring drug resistance. This further provides the possibility for generating novel targets to overcome therapeutic resistance by controlling regulation of these cells. Hence, CSCs, as potential therapeutic targets, enable therapeutic development that effectively combat tumor progression.
However, regulatory challenges pertaining to approval and usage of stem cell therapies are anticipated to inhibit growth of the market. In addition, certain manufacturing and pharmacological issues associated with this cell therapy development is estimated to slow down the progress of the market during the forecast period.

Market Segmentation, Outlook & Viewpoint: Global Cancer Stem Cells Market


Mode of Action Market Segmentation & Outlook (Revenue, USD Million, 2014 - 2025)

Targeted Cancerous Stem Cells (CSCs)

By Anti-CSC Therapeutics

Pathway Inhibitors

WNT Signaling Pathway

Hedgehog Signaling Pathway

Notch Signaling Pathway

Others


Surface Marker-based

Immuno-evasion & Targeting Tumor Microenvironment

Nanoparticle-based Therapies

Others


Products

Cell-Culturing

Cell-Separation

Cell Analysis

Molecular Analysis

Others



Stem Cell-based Cancer Therapy

Autologous SC Transplant

Allogeneic SC Transplant



Cancer Forms Market Segmentation & Outlook (Revenue, USD Million, 2014 - 2025)

Breast

Blood

Lung

Brain

Colorectal

Pancreatic

Bladder

Liver

Others


Key Players, Recent Developments & Regional Insights: Global Cancer Stem Cells Market


Understanding the biology of these cells and their role in management of tumor progression, the market can be segmented into two models of tumor treatment based on the mode of action. The first model incorporates targeted CSCs using monoclonal antibodies, recombinant proteins, nanomaterials, and other natural compounds. Majority of commercially available drugs facilitate tumor shrinkage, but do not target the root cause of tumor progression, which may further result in relapse of tumor growth.
This factor is providing a significant push to the growth of the segment. Increasing research on CSCs biology and their key signaling pathways, microenvironment, and surface markers are enabling development of agents that target these aspects of CSCs to control their regulation. Out of these aspects, agents targeting key pathways accounted for a major share.
Several review articles have documented roles of these pathways in functioning of CSCs. The second model deploys stem cells for tissue regeneration, immuno-reconstitution, and delivery of anti-cancer therapeutics. This segment is further bifurcated into autologous and allogenic cell treatment. Autologous treatments captured the largest market share in 2016 in terms of revenue.
Factors such as advantages of autologous transplant, affordability, improved survival rate of patients, and increase in transplantation procedures are poised to contribute to the growth of the segment. However, it has been observed that many cell therapy companies are increasingly focusing on the development of allogeneic cellular therapy products. This is expected to result in noteworthy growth of this segment over the forecast period.
Cancer Forms Insights
The report has focused on the use of stem cells against wide spectrum of tumor forms including breast, blood, lung, brain, colorectal, pancreas, and bladder, liver, head & neck, ovarian, prostate, and gastric tumor.
Out of all the tumor forms, breast cancer commanded the leading share of the overall revenue in 2016 owing to its rising incidence and presence of relatively large number of stem cell therapeutics for this tumor type. Moreover, the fact that autologous transplant has taken chemotherapy to a next level is likely to supplement the growth of the segment. Furthermore, stem cell therapies have been found to be successful in combating cardiotoxicity observed in survivors.
 
The lung cancer segment is projected to experience significant growth over the forecast period. The growth of the segment can be attributed to ongoing developments to curb the rising incidence of lung malignance worldwide. In March 2016, a team of researchers at the Department of Cancer Biology, Mayo Clinic developed a combination therapy using auranofin, a rheumatoid arthritis drug, with an experimental targeted agent to hamper the growth of lung CSCs.

Regional Insights
North America was the leading revenue contributor of the cancer stem cells market in 2016 due to presence of a substantial number of organizations engaged in conducting R&D activities related to stem cell therapy. There are several internationally recognized hospitals and medical institutes, such as Cancer Treatment Centers of America at Midwestern Regional Medical Center, which offer stem cell transplant therapies.
Asia Pacific is expected to be a promising region in the arena owing to presence of several organizations in the region that focus on R&D of stem cells. Moreover, funding agencies are providing grants to research communities to accelerate their scientific research on cancer stem cells in Asian countries.
Global Cancer Stem Cells Market Share Insights
Thermo Fisher Scientific, Inc.; AbbVie, Inc.; Merck KGaA; Bionomics; Lonza; Stemline Therapeutics, Inc.; Miltenyi Biotec; PromoCell GmbH; MacroGenics, Inc.; OncoMed Pharmaceuticals, Inc.; Irvine Scientific; STEMCELL Technologies Inc.; Sino Biological Inc.; and BIOTIME, INC are some of the key players operating in the market. In order to keep pace with the growing popularity of stem cell therapy in clinical oncology, these firms are undertaking various endeavors to stay competitive. Strategic alliances, facility expansion, and broadening product pipeline are some of the key initiatives undertaken by these participants.

Key Insights Covered: Global Cancer Stem Cells Market
1.  North America, Europe, Asia Pacific, Middle East & Africa, Latin America market size (sales, revenue and growth rate) of Cancer Stem Cells industry.
2. Global major manufacturers' operating situation (sales, revenue, growth rate and gross margin) of Cancer Stem Cells industry.
3. Global major countries (United States, Canada, Germany, France, UK, Italy, Russia, Spain, China, Japan, Korea, India, Australia, New Zealand, Southeast Asia, Middle East, Africa, Mexico, Brazil, C. America, Chile, Peru, Colombia) market size (sales, revenue and growth rate) of Cancer Stem Cells industry.
4. SWOT analysis, New Project Investment Feasibility Analysis, Upstream raw materials and manufacturing equipment & Industry chain analysis of Cancer Stem Cells industry.
5. Global market size (sales, revenue) forecast by regions and countries from 2019 to 2024 of Cancer Stem Cells industry.

Research Methodology: Global Cancer Stem Cells Market

Data collection and base year analysis is done using data collection modules with large sample sizes. The market data is analyzed and forecasted using market statistical and coherent models. Also market share analysis and key trend analysis are the major success factors in the market report. To know more please Request a Sample Report.
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Supply Side Primary Contributors: Product Managers, Marketing Managers, C-Level Executives, Distributors, Market Intelligence, Regulatory Affairs Managers among other