Global Cryo-electron Microscopy Market By Product Type (300kV Cryo-EM, 200kV Cryo-EM, and 120kV Cryo-EM), By Application (Academic and Research Institute, Pharma and Biotech, CRO, and Others), and By Region - Global Forecast to 2029 (Includes Business Impact of COVID-19)

  • TBI323105
  • September 16, 2021
  • Global
  • 145 pages
  • Market.US

Report updated on 11th September, 2021: Global Cryo-electron Microscopy Market By Product Type (300kV Cryo-EM, 200kV Cryo-EM, and 120kV Cryo-EM), By Application (Academic and Research Institute, Pharma and Biotech, CRO, and Others), and By Region - Global Forecast to 2029 (Includes Business Impact of COVID-19)

Trusted Business Insights has published a comprehensive market research report on, Global Cryo-electron Microscopy Market by Product Type(300kV Cryo-EM, 200kV Cryo-EM, and 120kV Cryo-EM), By Application (Academic and Research Institute, Pharma and Biotech, CRO, and Others), and by Region -Global Forecast to 2030, which offers a holistic view of the global cryo-electron microscopy market through systematic segmentation that covers every aspect of the target market. The global cryo-electron microscopy market is projected to be US$ 556.6 Mn in 2020 to reach US$ 1305.64 Mn by 2030 at a CAGR of 8.9%. Cryo-electron microscopy is a type of transmission electron microscopy which allows for the specimen of interest to be viewed at cryogenic temperature. In other words, it is an electron microscopy tool applied to samples cooled to cryogenic temperatures and implanted in an environment of clear water. Over the years of improvement, it has become a valuable technique for viewing and studying the structures of different biological molecules. In 2017, Jacques Dubochet, Joachim Frank and Richard Henderson were awarded Nobel Prize in Chemistry for their effort in developing cryo-electron microscope (Cryo-EM), a tool which fires beams of electrons at proteins that have been frozen in solution, to presume the biomolecules structure. One of the significant benefits of Cryo-electron microscopy is that microscopic samples are required for the determination of its structure. Compared to other microscopy techniques, Cryo-electron microscopy still produces virtuous images. Therefore, the capability of a Cryo-electron microscope to provide an accurate and useful image of complex molecules in their original form and environment is likely to help the market growth. Also, increasing application of Cryo-electron microscopes in the area of biological science, material science, and other related sectors for sample preparation, sample screening, data acquisition, image processing, and structure validation is expected to boost the growth of Cryo-electron microscopy market during the forecasted years.

Global Cryo-electron Microscopy Market Revenue (US$ Mn), 2019“2029

Although Cryo-EM offers high overall magnification, one of the major disadvantages of Cryo-electron microscope that is it provides a very low signal to noise ratio. i.e., For biological macromolecules, the critical building blocks include carbon, hydrogen, oxygen, and nitrogen. Given that electron absorption of these molecules is very low, then there is little contrast of the resulting images that make it challenging to detect features of a given sample when viewing a few samples. Global Cryo-electron Microscopy market is segmented based on product type, application, and region. Based on product type, the market is segmented into 300kV Cryo-EM, 200kV Cryo-EM, and 120kV Cryo-EM. The 300kV Cryo-EM segment accounts for the majority share and is expected to witness significant share in terms of revenue over the forecast period, followed by 200kV Cryo-EM segment. Based on application, the market is segmented into academic and research institute, pharma and biotech, CRO, and others. The academic and research institute segment accounts for a majority share in the global cryo-electron microscopy market.

Global Cryo-electron Microscopy Market Attractiveness Index by Product Type, 2018

By region, the market is segmented into North America, Europe, APAC, South America and Middle East Africa. Based on the region, North America is the mature market due to robust healthcare infrastructure. Also, well-equipped diagnostic centers and a growing number of ongoing clinical trials in this region have given the Cryo-electron microscope market a lift. The Asia Pacific will make a stubborn impression on the overall Cryo-electron microscope market. Rapidly increasing medical tourism in the region, particularly in the developing countries of China and India, is expected to give the aid the regional as well as global growth Cryo-electron microscopy market. The research report on the global cryo-electron microscopy market includes profiles of some of the major companies such as Hitachi, Ltd. (Hitachi High Technologies), Thermo Fisher Scientific Inc. (FEI), Danaher Corporation (Leica Microsystems), Carl Zeiss AG, and JEOL Ltd.

Below are the active patents related to Cryo-electron Microscopy Market.

Patent Number: US6946657B2 Electron microscopy system Abstract A particle-optical apparatus is disclosed which combines the functions of an energy selector 27 and a beam splitter 21. The particle-optical apparatus is used in an electron microscopy system and serves to separate and superimpose, respectively, beam paths of a primary electron beam 11 and a secondary electron beam 13. Application File Date: 2003-08-01 Application Granted Date: 2005-09-20 Current Assignee: Carl Zeiss NTS GmbH Patent Number: US8487253B2 Scanning electron microscope Abstract An object of the present invention is to provide a scanning electron microscope suitable for monitoring apparatus conditions of the microscope itself, irrespective of the presence of charge-up, specimen inclination, and the like. In order to achieve the object, proposed is a scanning electron microscope including a function to monitor the apparatus conditions on the basis of information obtained with an electron beam reflected before reaching a specimen. Specifically, for example, while applying a negative voltage to the specimen to reflect the electron beam before the electron beam reaches the specimen, and simultaneously supplying a predetermined signal to a deflector for alignment, the scanning electron microscope monitors changes of the detected positions of the reflected electrons of the electron beam. If the above-mentioned predetermined signal is under the condition where an alignment is properly performed, the changes of the detected positions of the electrons reflect deviation of an axis. Application File Date: US8487253B2 Application Granted Date: 2013-07-16 Current Assignee: Hitachi High Tech Corp Patent Number: US8598527B2 Scanning transmission electron microscopy Abstract A scanning transmission electron microscope includes an electron beam source to generate an electron beam. Beam optics are provided to converge the electron beam to a probe, such as for example a longitudinally stretched probe. A stage is provided to hold a specimen in the path of the electron beam. The specimen may include one or more elongated objects, such as for example polymers to be sequenced. A beam scanner scans the electron beam across the specimen. A controller may define one or more scanning areas corresponding to the locations of the elongated objects, and control one or more of the beam scanner and stage to selectively scan the electron beam probe in the scanning areas. The controller may also tune the beam optics during imaging. One or more detectors are provided to detect electrons transmitted through the specimen to generate an image for each of the scanning areas. The controller may also analyze the one or more images to determine information regarding the specimen, such as for example to sequence a polymer. Application File Date: 2011-11-22 Application Granted Date: 2013-12-03 Current Assignee: Mochii Inc , MOCHII Inc (D/B/A VOXA)

Key Market Segments

By Type
  • 300kV Cryo-EM
  • 200kV Cryo-EM
  • 120kV Cryo-EM
By Application
  • Academic and Research Institute
  • Pharma and Biotech
  • CRO

Key Market Players included in the report:

  • Bruker
  • Carl Zeiss Meditec AG.
  • Cordouan Technologies SAS.
  • Creative Biostructure
  • Danaher Corporation (Leica Microsystems)
  • Delong Holdings Ltd.
  • FEI Co.
  • Gatan Inc.
  • Helmut Hund GmbH
  • Hitachi High-Tech Corporation
  • HORIBA Europe GmbH
  • JEOL Ltd.
  • Labomed Inc.
  • Meiji Techno
  • Nikon Corporation
  • Olympus Corporation
  • Oxford Instruments
  • Semilab Inc
  • Sphire
  • Structura Biotechnology Inc,
  • Thermo Fisher Scientific Inc. (FEI)
  • Zeiss

Below are the key development related to Cryo-electron Microscopy Market in 2020 and 2021.

July 2021: UMass Medical School receives $2.8 million grant for advanced cryo-EM microscope. Massachusetts Life Sciences Center funding supports Cryo-EM Core Facility at UMMS. Roger J. Davis, PhD, FRS, and the Cryo-EM Core facility at UMass Medical School have received $2.8 million from the Massachusetts Life Sciences Center (MLSC) for the purchase of an advanced Glacios cryo-electron microscope from Thermo Fisher Scientific.Source June 2021: $8.1m cryogenic-electron microscopy centre now open in New York. A new $8.1m cryogenic-electron microscopy centre has opened at the Hauptman-Woodward Medical Research Institute on the Buffalo Niagara Medical Campus. Established to accelerate the treatment of disease, the new facility features cryogenic-electron microscopy technology and will service the biotech and pharmaceutical industry sciences. An installed cryo-electron microscope will allow researchers and clinicians to take a unique look at proteins, which are the basic machinery of life and the targets of pharmaceuticals. Source January 2021: JEOL announces new cold field emission cryo-electron microscope: CRYO ARM™ 300 II. JEOL has announced the release of a new cold field emission cryo-electron microscope (cryo-EM), the CRYO ARM™ 300 II (JEM-3300). This new cryo-EM has been developed based on the concept of “Quick and easy to operate and get high-contrast and high-resolution images. Source

1.1 Introduction
1.2 Taxonomy
1.3 Drivers for Global Cryo-electron Microscopy Market
1.4 Restraints for Global Cryo-electron Microscopy Market
1.5 Opportunities for Global Cryo-electron Microscopy Market
1.6 PEST Analysis
1.7 PORTER’s Analysis
1.8 Macro-economic Factors
1.9 Opportunity Map Analysis

1.9.1 Optimistic Scenario
1.9.2 Likely Scenario
1.9.3 Conservative Scenario

1.10 Opportunity Orbits
1.11 Market Investment Feasibility Index
1.12 Regional Market Share and BPS Analysis
1.13 Cost Structure Analysis
1.14 Industry Chain Analysis
1.15 Global Cryo-electron Microscopy Pricing Analysis 
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